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Roles of tumor necrosis factor-α and interleukin-6 in regulating bone cancer pain via TRPA1 signal pathway and beneficial effects of inhibition of neuro-inflammation and TRPA1

BACKGROUND: Pain is one of the most common and distressing symptoms suffered by patients with progression of bone cancer; however, the mechanisms responsible for hyperalgesia are not well understood. The purpose of our current study was to determine contributions of the sensory signaling pathways of...

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Detalles Bibliográficos
Autores principales: Zhao, Ding, Han, Dong-Feng, Wang, Si-Si, Lv, Bing, Wang, Xu, Ma, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580714/
https://www.ncbi.nlm.nih.gov/pubmed/31144562
http://dx.doi.org/10.1177/1744806919857981