Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E(2)

Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens. Here, we discovered that MDV activates the fatty acid synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEFs). In addition, MDV-infected cells contained high levels...

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Detalles Bibliográficos
Autores principales: Boodhoo, Nitish, Kamble, Nitin, Kaufer, Benedikt B., Behboudi, Shahriar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580946/
https://www.ncbi.nlm.nih.gov/pubmed/30971474
http://dx.doi.org/10.1128/JVI.00352-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580946/
https://www.ncbi.nlm.nih.gov/pubmed/30971474
http://dx.doi.org/10.1128/JVI.00352-19

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