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Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E(2)
Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens. Here, we discovered that MDV activates the fatty acid synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEFs). In addition, MDV-infected cells contained high levels...
Autores principales: | Boodhoo, Nitish, Kamble, Nitin, Kaufer, Benedikt B., Behboudi, Shahriar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580946/ https://www.ncbi.nlm.nih.gov/pubmed/30971474 http://dx.doi.org/10.1128/JVI.00352-19 |
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