Deep Mutational Scan of the Highly Conserved Influenza A Virus M1 Matrix Protein Reveals Substantial Intrinsic Mutational Tolerance

Influenza A virus matrix protein M1 is involved in multiple stages of the viral infectious cycle. Despite its functional importance, our present understanding of this essential viral protein is limited. The roles of a small subset of specific amino acids have been reported, but a more comprehensive...

Descripción completa

Detalles Bibliográficos
Autores principales: Hom, Nancy, Gentles, Lauren, Bloom, Jesse D., Lee, Kelly K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Genetic Diversity and Evolution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580950/
https://www.ncbi.nlm.nih.gov/pubmed/31019050
http://dx.doi.org/10.1128/JVI.00161-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580950/
https://www.ncbi.nlm.nih.gov/pubmed/31019050
http://dx.doi.org/10.1128/JVI.00161-19

Ejemplares similares