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Asparagine Is a Critical Limiting Metabolite for Vaccinia Virus Protein Synthesis during Glutamine Deprivation

Viruses actively interact with host metabolism because viral replication relies on host cells to provide nutrients and energy. Vaccinia virus (VACV; the prototype poxvirus) prefers glutamine to glucose for efficient replication to the extent that VACV replication is hindered in glutamine-free medium...

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Detalles Bibliográficos
Autores principales: Pant, Anil, Cao, Shuai, Yang, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580962/
https://www.ncbi.nlm.nih.gov/pubmed/30996100
http://dx.doi.org/10.1128/JVI.01834-18