Alzheimer’s Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in Drosophila

Alzheimer’s disease (AD) is the most common form of dementia and is characterized by intracellular neurofibrillary tangles of hyperphosphorylated Tau, including the 0N4R isoform and accumulation of extracellular amyloid beta (Aβ) plaques. However, less than 5% of AD cases are familial, with many add...

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Detalles Bibliográficos
Autores principales: Higham, James P., Malik, Bilal R., Buhl, Edgar, Dawson, Jennifer M., Ogier, Anna S., Lunnon, Katie, Hodge, James J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581016/
https://www.ncbi.nlm.nih.gov/pubmed/31244615
http://dx.doi.org/10.3389/fncel.2019.00260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581016/
https://www.ncbi.nlm.nih.gov/pubmed/31244615
http://dx.doi.org/10.3389/fncel.2019.00260

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