Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression

OBJECTIVE: Alcoholic liver disease (ALD) is a leading cause of death among chronic liver diseases. However, its pathogenesis has not been completely established. MicroRNAs (miRNAs) are key contributors to liver diseases progression. This study investigated hepatocyte-abundant miRNAs dysregulated by...

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Detalles Bibliográficos
Autores principales: Heo, Mi Jeong, Kim, Tae Hyun, You, Jueng Soo, Blaya, Delia, Sancho-Bru, Pau, Kim, Sang Geon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581021/
https://www.ncbi.nlm.nih.gov/pubmed/29475852
http://dx.doi.org/10.1136/gutjnl-2017-315123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581021/
https://www.ncbi.nlm.nih.gov/pubmed/29475852
http://dx.doi.org/10.1136/gutjnl-2017-315123

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