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Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression

OBJECTIVE: Alcoholic liver disease (ALD) is a leading cause of death among chronic liver diseases. However, its pathogenesis has not been completely established. MicroRNAs (miRNAs) are key contributors to liver diseases progression. This study investigated hepatocyte-abundant miRNAs dysregulated by...

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Detalles Bibliográficos
Autores principales:	Heo, Mi Jeong, Kim, Tae Hyun, You, Jueng Soo, Blaya, Delia, Sancho-Bru, Pau, Kim, Sang Geon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581021/ https://www.ncbi.nlm.nih.gov/pubmed/29475852 http://dx.doi.org/10.1136/gutjnl-2017-315123

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