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In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes

[(11)C]SNAP-7941 and its radiofluorinated, fluoro-ethyl derivative [(18)F]FE@SNAP have been developed as the first positron emission tomography tracers for melanin-concentrating hormone receptor 1 (MCHR1) imaging. Accumulation of these MCHR1 PET-tracers in rat brown adipose tissue (BAT) in vivo prov...

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Detalles Bibliográficos
Autores principales: Balber, Theresa, Benčurová, Katarína, Kiefer, Florian Wolfgang, Kulterer, Oana Cristina, Klebermass, Eva-Maria, Egger, Gerda, Tran, Loan, Wagner, Karl-Heinz, Viernstein, Helmut, Pallitsch, Katharina, Spreitzer, Helmut, Hacker, Marcus, Wadsak, Wolfgang, Mitterhauser, Markus, Philippe, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581027/
https://www.ncbi.nlm.nih.gov/pubmed/31244769
http://dx.doi.org/10.3389/fendo.2019.00324