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Optimizing Vancomycin Dosing in Chronic Kidney Disease by Deriving and Implementing a Web-Based Tool Using a Population Pharmacokinetics Analysis

Background: Chronic kidney disease (CKD) patients requiring intravenous vancomycin bear considerable risks of adverse outcomes both from the infection and vancomycin therapy itself, necessitating especially precise dosing to avoid sub- and supratherapeutic vancomycin exposure. Methods: In this retro...

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Detalles Bibliográficos
Autores principales: Dorajoo, Sreemanee Raaj, Winata, Chrystal Leandra, Goh, Jessica Hui Fen, Ooi, Say Tat, Somani, Jyoti, Yeoh, Lee Ying, Lee, Siok Ying, Yap, Chun Wei, Chan, Alexandre, Chae, Jung-woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581063/
https://www.ncbi.nlm.nih.gov/pubmed/31244657
http://dx.doi.org/10.3389/fphar.2019.00641