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Posttranslational Targeting of a Recombinant Protein Promotes Its Efficient Secretion into the Escherichia coli Periplasm

Many recombinant proteins that are produced in Escherichia coli have to be targeted to the periplasm to be functional. N-terminal signal peptides can be used to direct recombinant proteins to the membrane-embedded Sec translocon, a multiprotein complex that translocates proteins across the membrane...

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Detalles Bibliográficos
Autores principales: Ytterberg, A. Jimmy, Zubarev, Roman A., Baumgarten, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581171/
https://www.ncbi.nlm.nih.gov/pubmed/31003980
http://dx.doi.org/10.1128/AEM.00671-19