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Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension

Obesity is a common comorbidity for pulmonary arterial hypertension (PAH). Additionally, oestrogen and its metabolites are risk factors for the development of PAH. Visceral adipose tissue (VAT) is a major site of oestrogen production; however, the influence of obesity-induced changes in oestrogen sy...

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Detalles Bibliográficos
Autores principales: Mair, Kirsty M., Harvey, Katie Y., Henry, Alasdair D., Hillyard, Dianne Z., Nilsen, Margaret, MacLean, Margaret R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581204/
https://www.ncbi.nlm.nih.gov/pubmed/30923189
http://dx.doi.org/10.1183/13993003.01524-2018