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Awake (18)F-FDG PET Imaging of Memantine-Induced Brain Activation and Test–Retest in Freely Running Mice

PET scans of the mouse brain are usually performed with anesthesia to immobilize the animal. However, it is desirable to avoid the confounding factor of anesthesia in mouse-brain response. Methods: We developed and validated brain PET imaging of awake, freely moving mice. Head-motion tracking was pe...

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Detalles Bibliográficos
Autores principales: Miranda, Alan, Glorie, Dorien, Bertoglio, Daniele, Vleugels, Jochen, De Bruyne, Guido, Stroobants, Sigrid, Staelens, Steven, Verhaeghe, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581220/
https://www.ncbi.nlm.nih.gov/pubmed/30442754
http://dx.doi.org/10.2967/jnumed.118.218669