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Safety and immunogenicity of a killed bivalent (O1 and O139) whole-cell oral cholera vaccine in adults and children in Vellore, South India

This open-label study assessed the safety and immunogenicity of two doses (14 days apart) of an indigenously manufactured, killed, bivalent (Vibrio cholerae O1 and O139), whole-cell oral cholera vaccine (SHANCHOL; Shantha Biotechnics) in healthy adults (n = 100) and children (n = 100) in a cholera e...

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Detalles Bibliográficos
Autores principales: Raghava Mohan, Venkata, Raj, Santosh, Dhingra, Mandeep Singh, Aloysia D’Cor, Naveena, Singh, Ajit Pal, Saluja, Tarun, Kim, Deok Ryun, Midde, Venkat Jayanth, Kim, Yanghee, Vemula, Sridhar, Narla, Santhosh Kumar, Sah, Binod, Ali, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581248/
https://www.ncbi.nlm.nih.gov/pubmed/31211792
http://dx.doi.org/10.1371/journal.pone.0218033