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Mechanistic investigation of Ca(2+) alternans in human heart failure and its modulation by fibroblasts
BACKGROUND: Heart failure (HF) is characterized, among other factors, by a progressive loss of contractile function and by the formation of an arrhythmogenic substrate, both aspects partially related to intracellular Ca(2+) cycling disorders. In failing hearts both electrophysiological and structura...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581251/ https://www.ncbi.nlm.nih.gov/pubmed/31211790 http://dx.doi.org/10.1371/journal.pone.0217993 |