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A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters

Nipah virus (NiV) is a highly pathogenic re-emerging virus that causes outbreaks in South East Asia. Currently, no approved and licensed vaccine or antivirals exist. Here, we investigated the efficacy of ChAdOx1 NiV(B), a simian adenovirus-based vaccine encoding NiV glycoprotein (G) Bangladesh, in S...

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Detalles Bibliográficos
Autores principales: van Doremalen, Neeltje, Lambe, Teresa, Sebastian, Sarah, Bushmaker, Trenton, Fischer, Robert, Feldmann, Friederike, Haddock, Elaine, Letko, Michael, Avanzato, Victoria A., Rissanen, Ilona, LaCasse, Rachel, Scott, Dana, Bowden, Thomas A., Gilbert, Sarah, Munster, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581282/
https://www.ncbi.nlm.nih.gov/pubmed/31170144
http://dx.doi.org/10.1371/journal.pntd.0007462