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Sister centromere fusion during meiosis I depends on maintaining cohesins and destabilizing microtubule attachments

Sister centromere fusion is a process unique to meiosis that promotes co-orientation of the sister kinetochores, ensuring they attach to microtubules from the same pole during metaphase I. We have found that the kinetochore protein SPC105R/KNL1 and Protein Phosphatase 1 (PP1-87B) regulate sister cen...

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Detalles Bibliográficos
Autores principales: Wang, Lin-Ing, Das, Arunika, McKim, Kim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581285/
https://www.ncbi.nlm.nih.gov/pubmed/31150390
http://dx.doi.org/10.1371/journal.pgen.1008072