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High levels of cell-free DNA accurately predict late acute kidney injury in patients after cardiac surgery

Use of cardiopulmonary bypass in cardiac surgery triggers systemic inflammation by neutrophil activation leading to neutrophil extracellular traps (NETs) release. Hence, nuclear DNA released by necrotic and apoptotic cells might contribute to an increase in circulating cell-free DNA (cfDNA). cfDNA/N...

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Detalles Bibliográficos
Autores principales: Merkle, Julia, Daka, Aldo, Deppe, Antje C., Wahlers, Thorsten, Paunel-Görgülü, Adnana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581428/
https://www.ncbi.nlm.nih.gov/pubmed/31211810
http://dx.doi.org/10.1371/journal.pone.0218548