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RNAi-based functional selection identifies novel cell migration determinants dependent on PI3K and AKT pathways
Lentiviral short hairpin RNA (shRNA)-mediated genetic screening is a powerful tool for identifying loss-of-function phenotype in mammalian cells. Here, we report the identification of 91 cell migration-regulating genes using unbiased genome-wide functional genetic selection. Individual knockdown or...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581447/ https://www.ncbi.nlm.nih.gov/pubmed/25347953 http://dx.doi.org/10.1038/ncomms6217 |