CD4 T Cells Induce A Subset of MHCII-Expressing Microglia that Attenuates Alzheimer Pathology

Microglia play a key role in innate immunity in Alzheimer disease (AD), but their role as antigen-presenting cells is as yet unclear. Here we found that amyloid β peptide (Aβ)-specific T helper 1 (Aβ-Th1 cells) T cells polarized to secrete interferon-γ and intracerebroventricularly (ICV) injected to...

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Detalles Bibliográficos
Autores principales: Mittal, Kritika, Eremenko, Ekaterina, Berner, Omer, Elyahu, Yehezqel, Strominger, Itai, Apelblat, Daniella, Nemirovsky, Anna, Spiegel, Ivo, Monsonego, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581663/
https://www.ncbi.nlm.nih.gov/pubmed/31203186
http://dx.doi.org/10.1016/j.isci.2019.05.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581663/
https://www.ncbi.nlm.nih.gov/pubmed/31203186
http://dx.doi.org/10.1016/j.isci.2019.05.039

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