Non-canonical Hedgehog Signaling Pathway in Cancer: Activation of GLI Transcription Factors Beyond Smoothened

The Hedgehog-GLI (HH-GLI) pathway is a highly conserved signaling that plays a critical role in controlling cell specification, cell–cell interaction and tissue patterning during embryonic development. Canonical activation of HH-GLI signaling occurs through binding of HH ligands to the twelve-pass t...

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Detalles Bibliográficos
Autores principales: Pietrobono, Silvia, Gagliardi, Sinforosa, Stecca, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581679/
https://www.ncbi.nlm.nih.gov/pubmed/31244888
http://dx.doi.org/10.3389/fgene.2019.00556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581679/
https://www.ncbi.nlm.nih.gov/pubmed/31244888
http://dx.doi.org/10.3389/fgene.2019.00556

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