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Insulin Signaling and Insulin Resistance Facilitate Trained Immunity in Macrophages Through Metabolic and Epigenetic Changes

Adaptation of the innate immune system has been recently acknowledged, explaining sustained changes of innate immune responses. Such adaptation is termed trained immunity. Trained immunity is initiated by extracellular signals that trigger a cascade of events affecting cell metabolism and mediating...

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Detalles Bibliográficos
Autores principales: Ieronymaki, Eleftheria, Daskalaki, Maria G., Lyroni, Konstantina, Tsatsanis, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581697/
https://www.ncbi.nlm.nih.gov/pubmed/31244863
http://dx.doi.org/10.3389/fimmu.2019.01330