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Identification of the small molecule compound which induces hepatic differentiation of human mesenchymal stem cells

Human mesenchymal stem cells (MSCs) are expected to have utility as a cell source in regenerative medicine. Because we previously reported that suppression of the Wnt/β-catenin signal enhances hepatic differentiation of human MSCs, we synthesized twenty-three derivatives of small molecule compounds...

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Detalles Bibliográficos
Autores principales: Itaba, Noriko, Sakabe, Tomohiko, Kanki, Keita, Azumi, Junya, Shimizu, Hiroki, Kono, Yohei, Matsumi, Yoshiaki, Abe, Ken-ichiro, Tonoi, Takayuki, Oka, Hiroyuki, Sakurai, Toshihiko, Saimoto, Hiroyuki, Morimoto, Minoru, Mabuchi, Yo, Matsuzaki, Yumi, Shiota, Goshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581787/
https://www.ncbi.nlm.nih.gov/pubmed/31245457
http://dx.doi.org/10.1016/j.reth.2015.10.001