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Improved contractile force generation of tissue-engineered skeletal muscle constructs by IGF-I and Bcl-2 gene transfer with electrical pulse stimulation

INTRODUCTION: Tissue-engineered skeletal muscle constructs should be designed to generate contractile force with directional movement. Because electrical impulses from a somatic nervous system are crucial for in vivo skeletal muscle development, electrical pulse stimulation (EPS) culture as an artif...

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Detalles Bibliográficos
Autores principales: Ikeda, Kazushi, Ito, Akira, Sato, Masanori, Kawabe, Yoshinori, Kamihira, Masamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581813/
https://www.ncbi.nlm.nih.gov/pubmed/31245471
http://dx.doi.org/10.1016/j.reth.2015.12.004