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Heterogeneous filament network formation by myosin light chain isoforms effects on contractile energy output of single cardiomyocytes derived from human induced pluripotent stem cells

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) are expected to play an important role in heart therapies, in which hiPSC-CMs should generate sufficient contractile force to pump blood. However, recent studies have shown that the contractility of myocardial mimics compos...

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Detalles Bibliográficos
Autores principales: Mizutani, Takeomi, Furusawa, Kazuya, Haga, Hisashi, Kawabata, Kazushige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581838/
https://www.ncbi.nlm.nih.gov/pubmed/31245478
http://dx.doi.org/10.1016/j.reth.2016.02.009