Cargando…

Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase

Type II toxin-antitoxin (TA) modules encode a stable toxin that inhibits cell growth and an unstable protein antitoxin that neutralizes the toxin by direct protein-protein contact. hipBA of Escherichia coli strain K-12 codes for HipA, a serine-threonine kinase that phosphorylates and inhibits glutam...

Descripción completa

Detalles Bibliográficos
Autores principales: Vang Nielsen, Stine, Turnbull, Kathryn Jane, Roghanian, Mohammad, Bærentsen, Rene, Semanjski, Maja, Brodersen, Ditlev E., Macek, Boris, Gerdes, Kenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581861/
https://www.ncbi.nlm.nih.gov/pubmed/31213559
http://dx.doi.org/10.1128/mBio.01138-19