Regulation of CAR T cell-mediated cytokine release syndrome-like toxicity using low molecular weight adapters

Although chimeric antigen receptor (CAR) T cell therapies have demonstrated considerable success in treating hematologic malignancies, they have simultaneously been plagued by a cytokine release syndrome (CRS) that can harm or even kill the cancer patient. We describe a CAR T cell strategy in which...

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Detalles Bibliográficos
Autores principales: Lee, Yong Gu, Chu, Haiyan, Lu, Yingjuan, Leamon, Christopher P., Srinivasarao, Madduri, Putt, Karson S., Low, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581910/
https://www.ncbi.nlm.nih.gov/pubmed/31213606
http://dx.doi.org/10.1038/s41467-019-10565-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581910/
https://www.ncbi.nlm.nih.gov/pubmed/31213606
http://dx.doi.org/10.1038/s41467-019-10565-7

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