Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid β aggregation by increasing monoamine secretion

A new mechanism is revealed by which a polyphenol, rosmarinic acid (RA), suppresses amyloid β (Aβ) accumulation in mice. Here we examined the brains of mice (Alzheimer’s disease model) using DNA microarray analysis and revealed that the dopamine (DA)-signaling pathway was enhanced in the group fed R...

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Detalles Bibliográficos
Autores principales: Hase, Tomoki, Shishido, Syun, Yamamoto, So, Yamashita, Rei, Nukima, Haruka, Taira, Shu, Toyoda, Tsudoi, Abe, Keiko, Hamaguchi, Tsuyoshi, Ono, Kenjiro, Noguchi-Shinohara, Moeko, Yamada, Masahito, Kobayashi, Shoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581955/
https://www.ncbi.nlm.nih.gov/pubmed/31213631
http://dx.doi.org/10.1038/s41598-019-45168-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581955/
https://www.ncbi.nlm.nih.gov/pubmed/31213631
http://dx.doi.org/10.1038/s41598-019-45168-1

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