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Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid β aggregation by increasing monoamine secretion
A new mechanism is revealed by which a polyphenol, rosmarinic acid (RA), suppresses amyloid β (Aβ) accumulation in mice. Here we examined the brains of mice (Alzheimer’s disease model) using DNA microarray analysis and revealed that the dopamine (DA)-signaling pathway was enhanced in the group fed R...
Autores principales: | Hase, Tomoki, Shishido, Syun, Yamamoto, So, Yamashita, Rei, Nukima, Haruka, Taira, Shu, Toyoda, Tsudoi, Abe, Keiko, Hamaguchi, Tsuyoshi, Ono, Kenjiro, Noguchi-Shinohara, Moeko, Yamada, Masahito, Kobayashi, Shoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581955/ https://www.ncbi.nlm.nih.gov/pubmed/31213631 http://dx.doi.org/10.1038/s41598-019-45168-1 |
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