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Locally advanced rectal cancer transcriptomic-based secretome analysis reveals novel biomarkers useful to identify patients according to neoadjuvant chemoradiotherapy response

Most patients with locally advanced rectal cancer (LARC) present incomplete pathological response (pIR) to neoadjuvant chemoradiotherapy (nCRT). Despite the efforts to predict treatment response using tumor-molecular features, as differentially expressed genes, no molecule has proved to be a strong...

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Detalles Bibliográficos
Autores principales: Canto, Luisa Matos do, Cury, Sarah Santiloni, Barros-Filho, Mateus Camargo, Kupper, Bruna Elisa Catin, Begnami, Maria Dirlei Ferreira de Souza, Scapulatempo-Neto, Cristovam, Carvalho, Robson Francisco, Marchi, Fabio Albuquerque, Olsen, Dorte Aalund, Madsen, Jonna Skov, Havelund, Birgitte Mayland, Aguiar, Samuel, Rogatto, Silvia Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582145/
https://www.ncbi.nlm.nih.gov/pubmed/31213644
http://dx.doi.org/10.1038/s41598-019-45151-w