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Locally advanced rectal cancer transcriptomic-based secretome analysis reveals novel biomarkers useful to identify patients according to neoadjuvant chemoradiotherapy response
Most patients with locally advanced rectal cancer (LARC) present incomplete pathological response (pIR) to neoadjuvant chemoradiotherapy (nCRT). Despite the efforts to predict treatment response using tumor-molecular features, as differentially expressed genes, no molecule has proved to be a strong...
Autores principales: | Canto, Luisa Matos do, Cury, Sarah Santiloni, Barros-Filho, Mateus Camargo, Kupper, Bruna Elisa Catin, Begnami, Maria Dirlei Ferreira de Souza, Scapulatempo-Neto, Cristovam, Carvalho, Robson Francisco, Marchi, Fabio Albuquerque, Olsen, Dorte Aalund, Madsen, Jonna Skov, Havelund, Birgitte Mayland, Aguiar, Samuel, Rogatto, Silvia Regina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582145/ https://www.ncbi.nlm.nih.gov/pubmed/31213644 http://dx.doi.org/10.1038/s41598-019-45151-w |
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