Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk

Genetic studies of complex traits in animals have been hindered by the need to generate, maintain, and phenotype large panels of recombinant lines. We developed a new method, C. elegans eXtreme Quantitative Trait Locus (ceX-QTL) mapping, that overcomes this obstacle via bulk selection on millions of...

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Detalles Bibliográficos
Autores principales: Burga, Alejandro, Ben-David, Eyal, Lemus Vergara, Tzitziki, Boocock, James, Kruglyak, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582151/
https://www.ncbi.nlm.nih.gov/pubmed/31213597
http://dx.doi.org/10.1038/s41467-019-10636-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582151/
https://www.ncbi.nlm.nih.gov/pubmed/31213597
http://dx.doi.org/10.1038/s41467-019-10636-9

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