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Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk
Genetic studies of complex traits in animals have been hindered by the need to generate, maintain, and phenotype large panels of recombinant lines. We developed a new method, C. elegans eXtreme Quantitative Trait Locus (ceX-QTL) mapping, that overcomes this obstacle via bulk selection on millions of...
Autores principales: | Burga, Alejandro, Ben-David, Eyal, Lemus Vergara, Tzitziki, Boocock, James, Kruglyak, Leonid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582151/ https://www.ncbi.nlm.nih.gov/pubmed/31213597 http://dx.doi.org/10.1038/s41467-019-10636-9 |
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