Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress

Reactive oxygen species (ROS) are key regulators in cell proliferation, survival, tumor initiation and development. However, the role of ROS in tumor metastasis is less clear. Here, we show that oxidative stress inhibited tumor metastasis via activation of Hippo kinase MST1/2, which led to the phosp...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yang, Li, Juan, Gao, Ya, Luo, Yue, Luo, Hong, Wang, Liang, Yi, Yong, Yuan, Zengqiang, Jim Xiao, Zhi-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582208/
https://www.ncbi.nlm.nih.gov/pubmed/31212215
http://dx.doi.org/10.1016/j.redox.2019.101233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582208/
https://www.ncbi.nlm.nih.gov/pubmed/31212215
http://dx.doi.org/10.1016/j.redox.2019.101233

Ejemplares similares