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Hypoxia Imaging and Adaptive Radiotherapy: A State-of-the-Art Approach in the Management of Glioma

Severe hypoxia [oxygen partial pressure (pO(2)) below 5–10 mmHg] is more frequent in glioblastoma multiforme (GBM) compared to lower-grade gliomas. Seminal studies in the 1950s demonstrated that hypoxia was associated with increased resistance to low–linear energy transfer (LET) ionizing radiation....

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Detalles Bibliográficos
Autores principales: Gérard, Michael, Corroyer-Dulmont, Aurélien, Lesueur, Paul, Collet, Solène, Chérel, Michel, Bourgeois, Mickael, Stefan, Dinu, Limkin, Elaine Johanna, Perrio, Cécile, Guillamo, Jean-Sébastien, Dubray, Bernard, Bernaudin, Myriam, Thariat, Juliette, Valable, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582242/
https://www.ncbi.nlm.nih.gov/pubmed/31249831
http://dx.doi.org/10.3389/fmed.2019.00117