Transcriptome Responses to Dexamethasone Depending on Dose and Glucocorticoid Receptor Sensitivity in the Liver

Tissue sensitivity to glucocorticoids is a key factor dictating outcome of their homeostatic and therapeutic action, whereby liver represents one of the major peripheral targets. Here, we used pigs carrying a natural gain-of-function glucocorticoid receptor (GR) variant Ala610Val (GR(Ala610Val)) as...

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Detalles Bibliográficos
Autores principales: Murani, Eduard, Trakooljul, Nares, Hadlich, Frieder, Ponsuksili, Siriluck, Wimmers, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582245/
https://www.ncbi.nlm.nih.gov/pubmed/31249595
http://dx.doi.org/10.3389/fgene.2019.00559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582245/
https://www.ncbi.nlm.nih.gov/pubmed/31249595
http://dx.doi.org/10.3389/fgene.2019.00559

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