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Transcriptome Responses to Dexamethasone Depending on Dose and Glucocorticoid Receptor Sensitivity in the Liver
Tissue sensitivity to glucocorticoids is a key factor dictating outcome of their homeostatic and therapeutic action, whereby liver represents one of the major peripheral targets. Here, we used pigs carrying a natural gain-of-function glucocorticoid receptor (GR) variant Ala610Val (GR(Ala610Val)) as...
Autores principales: | Murani, Eduard, Trakooljul, Nares, Hadlich, Frieder, Ponsuksili, Siriluck, Wimmers, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582245/ https://www.ncbi.nlm.nih.gov/pubmed/31249595 http://dx.doi.org/10.3389/fgene.2019.00559 |
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