TET Upregulation Leads to 5-Hydroxymethylation Enrichment in Hepatoblastoma

Hepatoblastoma is an embryonal liver tumor carrying few genetic alterations. We previously disclosed in hepatoblastomas a genome-wide methylation dysfunction, characterized by hypermethylation at specific CpG islands, in addition to a low-level hypomethylation pattern in non-repetitive intergenic se...

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Detalles Bibliográficos
Autores principales: Rivas, Maria Prates, Aguiar, Talita Ferreira Marques, Fernandes, Gustavo Ribeiro, Caires-Júnior, Luiz Carlos, Goulart, Ernesto, Telles-Silva, Kayque Alves, Cypriano, Monica, de Toledo, Silvia Regina Caminada, Rosenberg, Carla, Carraro, Dirce Maria, da Costa, Cecilia Maria Lima, da Cunha, Isabela Werneck, Krepischi, Ana Cristina Victorino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582250/
https://www.ncbi.nlm.nih.gov/pubmed/31249594
http://dx.doi.org/10.3389/fgene.2019.00553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582250/
https://www.ncbi.nlm.nih.gov/pubmed/31249594
http://dx.doi.org/10.3389/fgene.2019.00553

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