Hedgehog Pathway Activation Alters Ciliary Signaling in Primary Hypothalamic Cultures

Primary cilia dysfunction has been associated with hyperphagia and obesity in both ciliopathy patients and mouse models of cilia perturbation. Neurons throughout the brain possess these solitary cellular appendages, including in the feeding centers of the hypothalamus. Several cell biology questions...

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Detalles Bibliográficos
Autores principales: Bansal, Ruchi, Engle, Staci E., Antonellis, Patrick J., Whitehouse, Logan S., Baucum, Anthony J., Cummins, Theodore R., Reiter, Jeremy F., Berbari, Nicolas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582312/
https://www.ncbi.nlm.nih.gov/pubmed/31249512
http://dx.doi.org/10.3389/fncel.2019.00266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582312/
https://www.ncbi.nlm.nih.gov/pubmed/31249512
http://dx.doi.org/10.3389/fncel.2019.00266

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