Ligands Exert Biased Activity to Regulate Sigma 1 Receptor Interactions With Cationic TRPA1, TRPV1, and TRPM8 Channels

The sigma 1 receptor (σ1R) and the mu-opioid receptor (MOR) regulate the transient receptor potential (TRP) V1 calcium channel. A series of proteins are involved in the cross-regulation between MORs and calcium channels like the glutamate N-methyl-D-aspartate receptor (NMDAR), including the histidin...

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Detalles Bibliográficos
Autores principales: Cortés-Montero, Elsa, Sánchez-Blázquez, Pilar, Onetti, Yara, Merlos, Manuel, Garzón, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582314/
https://www.ncbi.nlm.nih.gov/pubmed/31249525
http://dx.doi.org/10.3389/fphar.2019.00634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582314/
https://www.ncbi.nlm.nih.gov/pubmed/31249525
http://dx.doi.org/10.3389/fphar.2019.00634

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