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AlleleHMM: a data-driven method to identify allele specific differences in distributed functional genomic marks
How DNA sequence variation influences gene expression remains poorly understood. Diploid organisms have two homologous copies of their DNA sequence in the same nucleus, providing a rich source of information about how genetic variation affects a wealth of biochemical processes. However, few computat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582321/ https://www.ncbi.nlm.nih.gov/pubmed/30918970 http://dx.doi.org/10.1093/nar/gkz176 |