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AlleleHMM: a data-driven method to identify allele specific differences in distributed functional genomic marks

How DNA sequence variation influences gene expression remains poorly understood. Diploid organisms have two homologous copies of their DNA sequence in the same nucleus, providing a rich source of information about how genetic variation affects a wealth of biochemical processes. However, few computat...

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Detalles Bibliográficos
Autores principales: Chou, Shao-Pei, Danko, Charles G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582321/
https://www.ncbi.nlm.nih.gov/pubmed/30918970
http://dx.doi.org/10.1093/nar/gkz176