Primed adaptation tolerates extensive structural and size variations of the CRISPR RNA guide in Haloarcula hispanica

Recent studies on CRISPR adaptation revealed that priming is a major pathway of spacer acquisition, at least for the most prevalent type I systems. Priming is guided by a CRISPR RNA which fully/partially matches the invader DNA, but the plasticity of this RNA guide has not yet been characterized. In...

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Detalles Bibliográficos
Autores principales: Gong, Luyao, Li, Ming, Cheng, Feiyue, Zhao, Dahe, Chen, Yihua, Xiang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582329/
https://www.ncbi.nlm.nih.gov/pubmed/30957847
http://dx.doi.org/10.1093/nar/gkz244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582329/
https://www.ncbi.nlm.nih.gov/pubmed/30957847
http://dx.doi.org/10.1093/nar/gkz244

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