Cargando…
Primed adaptation tolerates extensive structural and size variations of the CRISPR RNA guide in Haloarcula hispanica
Recent studies on CRISPR adaptation revealed that priming is a major pathway of spacer acquisition, at least for the most prevalent type I systems. Priming is guided by a CRISPR RNA which fully/partially matches the invader DNA, but the plasticity of this RNA guide has not yet been characterized. In...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582329/ https://www.ncbi.nlm.nih.gov/pubmed/30957847 http://dx.doi.org/10.1093/nar/gkz244 |