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MSTD: an efficient method for detecting multi-scale topological domains from symmetric and asymmetric 3D genomic maps

The chromosome conformation capture (3C) technique and its variants have been employed to reveal the existence of a hierarchy of structures in three-dimensional (3D) chromosomal architecture, including compartments, topologically associating domains (TADs), sub-TADs and chromatin loops. However, exi...

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Detalles Bibliográficos
Autores principales: Ye, Yusen, Gao, Lin, Zhang, Shihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582338/
https://www.ncbi.nlm.nih.gov/pubmed/30941409
http://dx.doi.org/10.1093/nar/gkz201