Quantifying the two-state facilitated diffusion model of protein–DNA interactions

The current report extends the facilitated diffusion model to account for conflict between the search and recognition binding modes adopted by DNA-binding proteins (DBPs) as they search DNA and subsequently recognize and bind to their specific binding site. The speed of the search dynamics is govern...

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Detalles Bibliográficos
Autores principales: Leven, Itai, Levy, Yaakov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582340/
https://www.ncbi.nlm.nih.gov/pubmed/31045207
http://dx.doi.org/10.1093/nar/gkz308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582340/
https://www.ncbi.nlm.nih.gov/pubmed/31045207
http://dx.doi.org/10.1093/nar/gkz308

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