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Quantifying the two-state facilitated diffusion model of protein–DNA interactions
The current report extends the facilitated diffusion model to account for conflict between the search and recognition binding modes adopted by DNA-binding proteins (DBPs) as they search DNA and subsequently recognize and bind to their specific binding site. The speed of the search dynamics is govern...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582340/ https://www.ncbi.nlm.nih.gov/pubmed/31045207 http://dx.doi.org/10.1093/nar/gkz308 |