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A new role for Escherichia coli Dam DNA methylase in prevention of aberrant chromosomal replication

The Dam DNA methylase of Escherichia coli is required for methyl-directed mismatch repair, regulation of chromosomal DNA replication initiation from oriC (which is DnaA-dependent), and regulation of gene expression. Here, we show that Dam suppresses aberrant oriC-independent chromosomal replication...

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Detalles Bibliográficos
Autores principales: Raghunathan, Nalini, Goswami, Sayantan, Leela, Jakku K, Pandiyan, Apuratha, Gowrishankar, Jayaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582345/
https://www.ncbi.nlm.nih.gov/pubmed/30957852
http://dx.doi.org/10.1093/nar/gkz242