DNA sequence influences hexasome orientation to regulate DNA accessibility

Nucleosomes, the fundamental organizing units of eukaryotic genomes, contain ∼146 base pairs of DNA wrapped around a histone H3–H4 tetramer and two histone H2A–H2B dimers. Converting nucleosomes into hexasomes by removal of a H2A–H2B dimer is an important regulatory event, but its regulation and fun...

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Detalles Bibliográficos
Autores principales: Brehove, Matthew, Shatoff, Elan, Donovan, Benjamin T, Jipa, Caroline M, Bundschuh, Ralf, Poirier, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582347/
https://www.ncbi.nlm.nih.gov/pubmed/31216039
http://dx.doi.org/10.1093/nar/gkz283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582347/
https://www.ncbi.nlm.nih.gov/pubmed/31216039
http://dx.doi.org/10.1093/nar/gkz283

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