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Bacterial genome architecture shapes global transcriptional regulation by DNA supercoiling
DNA supercoiling acts as a global transcriptional regulator in bacteria, that plays an important role in adapting their expression programme to environmental changes, but for which no quantitative or even qualitative regulatory model is available. Here, we focus on spatial supercoiling heterogeneiti...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582348/ https://www.ncbi.nlm.nih.gov/pubmed/31216038 http://dx.doi.org/10.1093/nar/gkz300 |