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Bacterial genome architecture shapes global transcriptional regulation by DNA supercoiling

DNA supercoiling acts as a global transcriptional regulator in bacteria, that plays an important role in adapting their expression programme to environmental changes, but for which no quantitative or even qualitative regulatory model is available. Here, we focus on spatial supercoiling heterogeneiti...

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Detalles Bibliográficos
Autores principales: El Houdaigui, Bilal, Forquet, Raphaël, Hindré, Thomas, Schneider, Dominique, Nasser, William, Reverchon, Sylvie, Meyer, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582348/
https://www.ncbi.nlm.nih.gov/pubmed/31216038
http://dx.doi.org/10.1093/nar/gkz300