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A panel of colorimetric assays to measure enzymatic activity in the base excision DNA repair pathway

DNA repair is essential for the maintenance of genomic integrity, and evidence suggest that inter-individual variation in DNA repair efficiency may contribute to disease risk. However, robust assays suitable for quantitative determination of DNA repair capacity in large cohort and clinical trials ar...

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Detalles Bibliográficos
Autores principales: Healing, Eleanor, Charlier, Clara F, Meira, Lisiane B, Elliott, Ruan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582407/
https://www.ncbi.nlm.nih.gov/pubmed/30869144
http://dx.doi.org/10.1093/nar/gkz171